雷达模拟器目标威胁度评估方法研究

研究雷达模拟器目标威胁度的准确评估问题,是辅助操作手对空中目标进行打击的重要依据.威胁度普通雷达是难以探测的.由于目标的速度、距离等随机性强,具体数据难以确定.针对威胁度评估问题,多限于权重分析、聚类分析等方法,对难以确定的参数有较大依赖.为解决上述问题,提出应用效能指数的方法来确定未知目标对雷达阵地的威胁度,根据雷达能够获取的数据,得出判断矩阵,实现对雷达所测数据的分析,并评估目标的威胁度.上述方法可用于雷达模拟器,能够灵活地根据情况调整威胁度评估方法.实验结果表明,方法能够较好地在某些属性未知的情况下,可对目标威胁度进行准确评估,证明改进方法为威胁度评估提供了有效依据.     

基于Virtools的虚拟现实技术及在特种设备教学中的应用

本文以电梯为研究对象,运用虚拟现实技术建立电梯虚拟样机,开发了一种电梯零部件识别系统用于电梯司机的考核。现行的考核方式存在过程繁琐、成绩统计困难等问题,就这些问题提出了合理的解决方案,并将方案应用于开发的系统中。该系统是虚拟现实技术在特种设备领域的全新应用,构建的虚拟电梯完整地呈现了真实的电梯,而且可以从多角度观察其结构的每个细节,方便教学与考核。系统结合SolidWorks、3Dmax、Virtools等软件,以触摸选择为主要的操作方式,具有优良的操作性与交互性,且投资少、开发周期短。     

基于CPSO-BP神经网络的风电并网暂态电压稳定评估

针对目前传统方法难以快速、准确判断风电并网后系统暂态电压稳定性的问题,提出了一种基于CPSO-BP组合的风电并网暂态电压稳定评估方法。首先采用混沌理论对粒子群算法的不足进行改善,应用改进后的算法对神经网络的初始权值和阈值进行优化,然后利用系统故障前后采集的传统物理量和风电场相关的物理量作为BP神经网络输入特征量进行监督学习,最后将训练得到的模型应用于风电并网系统的暂态电压稳定评估中。利用英格兰10机39节点系统标准算例进行风电并网仿真分析,结果证明了所提方法的有效性。     

敏捷化AIOps框架及运维数据质量评估方法

敏捷化智能运维(AIOps)框架将模型构建提前至测试阶段,利用该阶段产生的监控数据代替线上采集的数据以训练AIOps模型,进而实现智能运维的早开发与早使用. 运维数据质量评估方法通过最大均值差异度量方式,分别在健康评估与故障诊断运维场景下对训练数据分别进行趋势性、阶段性、可检测性及可诊断性评估,以预估数据对模型的适用性. 基于华为技术有限公司提供的测试环境设置测试用例并构建实验数据集,在该数据集上的实验结果验证了敏捷化AIOps框架的可行性及数据质量评估方法的有效性.     

Well-Known and Novel Serum Biomarkers for Risk Stratification of Patients with Non-ischemic Dilated Cardiomyopathy

Non-ischemic dilated cardiomyopathy encompasses a wide spectrum of myocardial disorders, characterized by left ventricular dilatation with systolic impairment and increased risk of sudden cardiac death. In spite of all the therapeutic progress that has been made in recent years, dilated cardiomyopathy continues to be an important cause of cardiac transplant, being associated with an enormous cost burden for health care systems worldwide. Predicting the prognosis of patients with dilated cardiomyopathy is essential to individualize treatment. Late gadolinium enhancement-cardiac magnetic resonance imaging, microvolt T-wave alternans, and genetic testing have emerged as powerful tools in predicting sudden cardiac death occurrence and maximizing patient’s selection. Despite all these new diagnostic modalities, additional tests to complement or replace current tools are required for better risk stratification. Therefore, biomarkers are an easy and important tool that can help to detect patients at risk of adverse cardiovascular events. Additionally, identifying potential biomarkers involved in dilated cardiomyopathy can provide us important information regarding the diagnostic, prognostic, risk stratification, and response to treatment for these patients. Many potential biomarkers have been studied in patients with dilated cardiomyopathy, but only a few have been adopted in current practice. Therefore, the aim of our review is to provide the clinicians with an update on the well-known and novel biomarkers that can be useful for risk stratification of patients with non-ischemic dilated cardiomyopathy.     

The Causes and Potential Injurious Effects of Elevated Serum Leptin Levels in Chronic Kidney Disease Patients

Leptin is an adipokine that regulates appetite and body mass and has many other pleiotropic functions, including regulating kidney function. Increased evidence shows that chronic kidney disease (CKD) is associated with hyperleptinemia, but the reasons for this phenomenon are not fully understood. In this review, we focused on potential causes of hyperleptinemia in patients with CKD and the effects of elevated serum leptin levels on patient kidney function and cardiovascular risk. The available data indicate that the increased concentration of leptin in the blood of CKD patients may result from both decreased leptin elimination from the circulation by the kidneys (due to renal dysfunction) and increased leptin production by the adipose tissue. The overproduction of leptin by the adipose tissue could result from: (a) hyperinsulinemia; (b) chronic inflammation; and (c) significant lipid disturbances in CKD patients. Elevated leptin in CKD patients may further deteriorate kidney function and lead to increased cardiovascular risk.     

Effects of Berry Anthocyanins on Cognitive Performance,Vascular Function and Cardiometabolic Risk Markers: A Systematic Review of Randomized Placebo-Controlled Intervention Studies in Humans

Supplementation with anthocyanins, which are a type of flavonoids mainly found in various berries, is hypothesized to be a promising approach to lower the risk of developing cognitive decline. The aim of this systematic review was to provide a comprehensive overview of dietary intervention trials describing effects of berry anthocyanins on cognitive performance in humans, while also addressing potential underlying mechanisms. A total of 1197 articles were identified through a systematic search, and 49 studies reporting effects on cognitive performance (n = 18), vascular function (n = 22), or cardiometabolic risk markers (n = 32) were included. Significant improvements were observed on memory, while some of the studies also reported effects on attention and psychomotor speed or executive function. Vascular function markers such as brachial artery flow-mediated vasodilation were also affected and consistent evidence was provided for the beneficial effects of berry anthocyanins on endothelial function. Finally, studies reported improvements in blood pressure, but effects on metabolic risk markers (e.g. carbohydrate and lipid metabolism) were less consistent. In conclusion, this review provides evidence for the beneficial effects of berry anthocyanins on cognitive performance as memory improved. Whether observed anthocyanin-induced improvements in vascular function and blood pressure underlie beneficial effects on cognitive performance warrants further study.     

用ASP.NET开发基于Web的综合测评系统

利用ASP .NET技术构建基于Web的动态交互式综合测评系统 ,该系统可以在Windows 2 0 0 0 /XP局域网或Internet上使用 ,测评内容修改方便 ,适用范围广泛。     

An evaluation of the performance of an automated procedure for comparative modelling of protein tertiary structure

A 3-D model of a protein can be constructed from its amino acidsequence and the 3-D structures of one or more homologues byannealing three sets of fragments: the structurally conservedregions, structurally variable regions and the side chains.The method encoded in the computer program COMPOSER was assessedby generating 3-D models of eight proteins whose crystal structuresare already known and for which 3-D structures of homologuesare available. In the structurally conserved regions, differencesbetween modelled and X-ray structures are smaller than the differencesbetween the X-ray structures of the modelled protein and thehomologues used to build the model. When several homologuesare used, the contributions of the known structures are weighted,preferably by the square of sequence similarity; this is especiallyimportant when the similarities of the homologues to the modelledstructure differ greatly. The ‘collar’ extensionapproach, in which a similar region of different length in ahomologue is used to extend the framework, can result in a moreaccurate model. If known homologues comprise more than one relatedgroup of proteins and they are both distantly related to theunknown, then alignment of the sequence to be modelled witheach group of homologues facilitates identification of structurallyconserved regions of the unknown and leads to an improved model.Models have root mean square differences (r.m.s.d.s) with thestructures defined by X-ray analysis of between 0.73 and 1.56Å for all C atoms, for seven of the eight models. Forthe model of mucor pepsin, where the closest homologue has 33%sequence identity and 20% of the residues are in structurallyvariable regions, the r.m.s.d. for the framework region is 1.71Å and the r.m.s.d. for all C atoms is 3.47 Â.     

实践工程总承包之体会

介绍了目前国际上广为采用的5种工程总承包方式以及水泥工业建设项目总包工程合同管理和索赔管理的内容与要求;分析了设计单位进行工程总承包的优势所在;探讨了工程总包实施中各类风险。